EMOD papers

EMOD official documentation

IDM’s documentation

Software design of EMOD

(2018) Implementation and applications of EMOD, an individual-based multi-disease modeling platform

(2018) Agent-based models of malaria transmission: a systematic review

Mosquito model

(2011) A malaria transmission-directed model of mosquito life cycle and ecology

Within-host model

(2012) P. falciparum Infection Durations and Infectiousness Are Shaped by Antigenic Variation and Innate and Adaptive Host Immunity in a Mathematical Model

(2012) Malaria parasite diversity and transmission intensity affect development of parasitological immunity in a mathematical model

(2021) Mechanistic within-host models of the asexual Plasmodium falciparum infection: a review and analytical assessment

Within-host calibration and transmission

(2015) Calibration of an intrahost malaria model and parameter ensemble evaluation of a pre-erythrocytic vaccine (also has vaccine)

(2015) Characterization of the infectious reservoir of malaria with an agent-based model calibrated to age-stratified parasite densities and infectiousness (also has detectability and drug campaigns)

(2018) Seasonality and heterogeneity of malaria transmission determine success of interventions in high-endemic settings: a modeling study (also has IRS and drug campaigns)

(2018) Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings (sexual stage immunity)

Generic interventions

(2013) Mathematical Models of Within-Host and Transmission Dynamics to Determine Effects of Malaria Interventions in a Variety of Transmission Settings

Drug-based interventions

(2015) Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination (PKPD model)

(2017) Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study (multi-model)

(2018) Impact of mass drug administration campaigns depends on interaction with seasonal human movement

(2019) Reducing malaria burden and accelerating elimination with long-lasting systemic insecticides: a modelling study of three potential use cases (systemic insecticides)

Vaccines

(2013) A mathematical model of the impact of present and future malaria vaccines

(2016) Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models (multi-model)

Gene drives

(2016) Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics (gene drives alone)

(2021) Modeling impact and cost-effectiveness of driving-Y gene drives for malaria elimination in the Democratic Republic of the Congo (gene drives in combination with other interventions)

(2020) Vector genetics, insecticide resistance and gene drives: An agent-based modeling approach to evaluate malaria transmission and elimination (new gene drive model)

Zambia elimination (multi-intervention)

(2016) Optimal Population-Level Infection Detection Strategies for Malaria Control and Elimination in a Spatial Model of Malaria Transmission

(2016) Malaria Elimination Campaigns in the Lake Kariba Region of Zambia: A Spatial Dynamical Model

(2017) Effectiveness of reactive case detection for malaria elimination in three archetypical transmission settings: a modelling study

(2019) Effective strategies for preventing reestablishment of malaria in areas with recent elimination and high transmission potential